The blues will be approaching the match with high caution after a 4-1 demolition by Brentford in EPL on Saturday.
The Royal whites on the other hand appear confident after a 2-1 win over Celta De Vigo in the Spanish La Liga last weekend.
The clash is a replica of last season's semifinals clash and here are the possible starting players for the two teams.
Chelsea with a 3-4-2-1 formation: Edouard Mendy, Cesar Azpilicueta, Trevor Chalobah, Antonio Ruediger, Reece James, Ngolo Kante, Jorginho, Marcos Alonso, Hakim Ziyech, Christian Pulisic and Kai Havertz.
Players to watch here are Ziyech, Havertz, Kante and Mason Mount if he plays.
The Spanish giants will likely go with the 4-3-3 formation. Thibaut Curtois starts on the goal, Ferland Mendy, David Alaba, Eder Militao and Daniel Carvajal will be on the defence.
Toni Kroos, Casemiro and Luka Modric will be bossing the midfield as Vinicious Junior, Karim Benzema and Federico Valverde take the front.
Players to keep an eye on are Benzema and Vinicious as they will likely give Chelsea's defence problems with their pace.
Will Chelsea take the home advantage and get the job done or will Real Madrid get the better of them this time?
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