Ole Gunnar Solskjaer was filled with joy after thrashing the Saints recording home and away victory since their last tittle winning campaign.
It is the third time a team has lost nine goals in the Premier League, with United also beating Ipswich Town by that margin.
Aaron Wan Bissaka opened the scoring with his first goal at Old Trafford, Marcus Rashford who have been subjected to racism in their last match doubled United lead and Edinson Cavani also found the net. Jan Bednarek netted his own net before the break after a superb cross from Marcus Rashford.
Anthony Martial ended an eight match goal drought before Scott McTominay could net another goal.
Bednarek became the second Saints player to be sent off after a poor tackle on Anthony Martial to allow Bruno Fernandes the chance to score from the penalty spot. The French forward doubled netting his second goal.
Daniel James who had been dropped out for quite a while wrapped up the scoring in stoppage time.
Manchester United came back in different form not forgetting that the Red Devil's had their first victory in their last four matches.
Manchester United leveled the Points by premier league leaders Manchester City but the leaders are leading on goal difference and this is the only obstacle disallowing Manchester United to be in the first place.
Martial should be particularly pleased with his contribution, even though it did not match manager Ole Gunnar Solskjaer's four goal as substitute as a United substitute in an eight goals to one victory at Nottingham Forest.
Bruno Fernandes is merging to be breaking the records in English premier league , He have assisted fifteen Premier League goals as he marks his thirty six appearance in the competition, only former United striker Eric Cantona and Ex Wes Ham forward Dimitri Payet have the same statistics but with thirty three appearance for each one of them.
Rashford and McTominay both produced astonishing strikes for a United side that also had a penalty award overturned just before half time.
Jankewitz made his premier league debut that later tourned sour after a anticipated defeat by the red devil's.
He was sent off second minutes in the first half of the game on committing a faul on Scott McTominay in front of his manager Ralph Hassenhuttl. The nineteen year old Swiss midfielder had booked a red card, Ralph was calm after witnessing the incident.
Jankewitz's agent had started looking forward on a potential transfer after complaining lack of playing minutes claiming Jankewitz has not been subjected at St Mary's. The pressure of Jankewitz's agent end result was portrayed in the first half of the match.
After the incident, it was just a question of how long the visitors could survive, which turned out to be not very long after Wan Bissaka turned in Luke Shaw's cross at the far post from a position Jankewitz should have been defending.
Bednarek among the scorers after turning Rashford's cross into his own net for the third goal,Che Adams thought he had had utilized the chance netting at the start of the second half but was dissolved after VAR. Unfortunately that wasn't the end of the misery.
Ralph Hassenhuttl "Jankewitz's dismissal as the key moment,there can be no excusing the team though badly affected by injuries.
Unfortunately that was not the end of the misery.
One man down after three minutes against this opponent , congratulations to Manchester United, they worked us off and did not stop scoring. The second red card is most disappointing,we don't have any more players.
We tried in the second half to keep a clean sheet as much as we could, but at nine men it was too easy for them to score.
What can I say? It is horrible. But we stood up after the first nine goals against Leicester and we have to do that again."
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