Aston Villa, on the other hand, will do all in their power to climb the league table after a fantastic performance against Everton last weekend.
The match will take place at Old Trafford at 12:30 p.m. West African time, with fans allowed into the stadium.
STATISTICS IN COMPARISON,
Manchester United has played Aston Villa in 190 games, winning 101, drawing 40, and losing 49. They have won three and lost one of their last four matches with the Villa.
The last time Aston Villa won at Old Trafford was in 2009, following Cristiano Ronaldo's transfer to Real Madrid. With his return, the story will undoubtedly change.
In all competitions, Manchester United has won four, drawn one, and lost two of their seven matches. With four victories and a tie in the Premier League, they remain unblemished.
Their two defeats came in the UEFA Champions League and the Carabao Cup. They were defeated 1-0 by West Ham United in the Carabao Cup at Old Trafford recently. They are currently in third place in the EPL standings, with 13 points.
In contrast, Aston Villa has won two, drawn two, and lost two of their six matches in all competitions. Their most recent match came in the Carabao Cup, when they were defeated by Chelsea in a penalty shootout.
After five games, they are in tenth place in the English Premier League standings with eight points.
Stats on the Major Players
Cristiano Ronaldo, Manchester United's goal machine, will be eager to march into Old Trafford and get the game started after his incredible form against this team.
Cristiano has played 14 times against them, winning 13 occasions and drawing once. In those games, he has a total of nine goals and three assists.
He has currently scored in all of Manchester United's games that he has started. For the Red Devils, he has four goals in all competitions, three of which have come in the Premier League.
Danny Ings was signed by Aston Villa from Southampton during the summer transfer window. In his two appearances on the field for the club, Ings had two goals and two assists.
August's goal of the month was his overhead kick debut goal.
Manchester United has fewer injury problems, with Marcus Rashford and Amad Traore the only players who have been injured.
Aston Villa will be missing Leon Bailey, who suffered a quad injury in last weekend's 3-0 win against Everton.
In that stunning victory over the Toffees, he scored the third goal.
Trezeguet, who has been out with a knee injury since April, is another doubt for the Aston Villa side.
Mike Dean, the famed referee in the middle of the pitch, will be the official for this match.
He'll be officiating with Darren Cann as his partner and Eddie Smart as his assistant.
The fourth official will be Michael Salisbury.
The VAR will be overseen by Andy Madley.
Manchester United is expected to defeat Aston Villa 3-1, with Cristiano Ronaldo scoring once again.
What do you think the outcome will be? Let's talk about it in the comments' section below:
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