Karen-Gataka-Rongai Road traffic police commander Justus Kent who confirmed the incident said the Friday evening accident took place at 5pm.
According to Justus, their lorry was transporting poles to a hardware shop in Rongai in Nairobi County before the lorry overturned.
"The accident happened at around 5pm. The lorry had five occupants onboard. Three farmers lost lives on the spot, while two others sustained serious injuries," Justus said.
The police boss said the lorry had developed a tyre burst when it overtuned and rolled several times.
The injured has been rushed to Nairobi County hospital for medical treatment.
The bodies of the three people have been transferred to Chiromo hospital morgue pending identification.
The security officers around the area has closed the road indefinitely to allow room for towing of the lorry wreckage away from the road.
Police investigations is also underway.
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