He suspended learning in schools, religious gatherings and public transport between districts for a period of 42 days.
Parents at Kyebambe Girls High School pick up their children following government's directive to close all schools for 42 days.
This was after 1,259 new positive cases and nine more deaths were announced by the Ministry of Health on Sunday.
The total number of recorded infections since the outbreak was announced on March last year now stands at 52,935.
The president attributed the new wave to people failing to comply to the orders by the government.
Getting vaccinated is one of the ways in curbing the virus but the situation is very different in Uganda.
As per the reports from the Uganda MOH, only thirty thousand people had received the second dose of the vaccines.
This is a very small figure when compared to the 21.9 million target announced by Museveni yesterday.
The president had in February promised the people of Uganda total freedom if 5 million get the jabs.
IN its editorial carton section today, Daily Monitor mocked the vaccination by comparing its rate with the speed of a snail.
Readers of the paper could not deny that it was a perfect picture to sum the situation.
Below are some of their comments.
Koller Hiob: Stop creating panic, new agencies and their over true stories.
Milly Boganza: I am not taking any dose.
Kenneth Ivans: Atwine legs though, you will not see heaven.
Bumba Erinest: Out of 40M Ugandans!
James Oyom: Uganda is a joking country and they need over 500,000 teachers to get their first and second jabs within 42 days.
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