Stay away from spiders they are dangerous.
Many spiders aren't poisonous. Bites can sometimes be severe and develop late. Poisonous spiders, such as black widows and brown recluses, generally live in undisturbed areas, such as attics or sheds, and don't bite unless threatened.
There is only one aggressive spider named funnel-web in Australia, which attacks the human being without provocation. The majority of venomous spiders are found in Latin America. These large spiders are quite aggressive and their venom is pharmacologically highly toxic. Their bite results in severe pain, neurotoxic effects, diaphoresis, severe allergic reaction and priapism . Other spiders normally exhibit aggressive behavior after being trapped, injured or provoked. The severity of reactions to spider venom depends on factors such as its amount, site of biting and its duration and age and health condition. Mortality due to spider bite is rare . Spider venom includes different peptides and substances affecting sodium, calcium and potassium channels in neurons and also glutamate and acetylcholine receptors .Spider bite victims develop symptoms such as pain and swelling in the site of biting, necrosis, pyrexia, pulmonary edema, respiratory distress, hypertension, kidney dysfunction and death. Treatment protocol in the case of critically ill patients includes supportive measures and antivenom injection. Respiratory support and monitoring the hemodynamic status of these patients are of fundamental importance . Highly venomous spiders, funnel-web in Australia and armadeiras (armed spiders) in South America require antivenom and intensive therapeutic interventions . Three important syndromes are caused by spider bites: latrodectism, loxoscelism, and funnel-web spider syndrome .
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